Merck Purospher® HPLC Columns

LE-Purospher

The Total Solution for HPLC Separations

Purospher® HPLC columns are based on high purity, metal-free silica for outstanding separations with excellent peak symmetry. This makes them the ideal choice for modern Reverse Phase HPLC.
The base silica for Purospher® high purity HPLC columns is made from tetraalkoxysilane in a sol-gel process. Thanks to the absence of metals in the silica matrix, and an optimized surface coating and shielding process, Purospher® columns provide tailing-free separations of acidic, basic, and chelating compounds. This is of particular advantage for any kind of method development in Research and Development (R&D) and Quality Control (QC) laboratories.

Features and Benefits

  • Enhanced performance and excellent peak symmetry due to high
  • purity silica gel
  • Outstanding batch-to-batch reproducibility for reliable analyses
  • Balanced chromatographic properties (Tanaka Hexagon)
  • Excellent separation efficiency for reliable results
  • Extended column lifetime for higher laboratory efficiency

Specifications : Specification of Purospher®

Purospher® Product Family

A complete range of Purospher® columns is available to suit a variety of separation requirements.

Purospher® RP-18 is polar endcapped and suitable for separations of strong basic or chelating compounds (not acidic compounds) and separations of hydrophilic compounds with a high percentage of water in the mobile phase.

Purospher® RP-18 endcapped is suitable for separations of complex samples with simple eluents.

Purospher® RP-18 HC is not endcapped with very good suitability for separation of polar, not basic compounds e.g. explosives.

Purospher® STAR RP-18 endcapped allows the tailing-free separation of neutral, acidic, basic or chelating compounds. The excellent stability up to pH 10.5 enables the separation of strong basic compounds with alkaline eluents. Purospher® STAR RP-18 endcapped is available in different particle sizes of 2µm, 3µm and 5µm and as special UHPLC columns.

Purospher® STAR RP-18 Endcapped UHPLC for tailing-free separations of neutral, acidic, basic or chelating compounds. Excellent stability up to pH 10.5 enables the separation of strong basic compounds with alkaline eluents.

Purospher® STAR RP-8 endcapped for separation of polar compounds or separation of position isomeric compounds.

Purospher® STAR NH2 and Si for Normal phase Chromatography (Si) and separation of carbohydrates (NH2).